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Primaquine Drug Interactions

Other Antimalarials
Taking primaquine with other antimalarial medications may lead to serious reactions, including the risk for seizures or QT prolongation, a dangerous type of arrhythmia. It should be noted that primaquine is often used in combination with other antimalarial drugs. However, these medications should only be taken together if prescribed by a healthcare provider.
 
Ramelteon
Taking primaquine with ramelteon may increase the amount of ramelteon in the body, potentially increasing your risk for side effects, such as extreme sedation. Talk to your healthcare provider before taking these medications together. You may need a different dose of ramelteon.
 
Ropinirole
Primaquine may increase the levels of ropinirole in your body, increasing your risk for side effects. If you take these medications together, your healthcare provider may need to monitor you more closely for ropinirole side effects.
 
Tizanidine
Taking primaquine with tizanidine may increase the levels of tizanidine in your body. This may increase your risk of tizanidine side effects. Your healthcare provider may need to adjust your tizanidine dose if you take primaquine.
 
Theophylline
Primaquine may increase the level of theophylline in your body, which may be dangerous. If you take these medications together, your healthcare provider may need to monitor you more closely and adjust your theophylline dose if necessary.
 

Final Thoughts

It is possible that not all primaquine drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about specific interactions that may apply to you.
 
It is always a good idea to give your healthcare provider a complete list of all medications you are taking, including prescription drugs, nonprescription drugs, herbs, and supplements.
 

Primaquine Medication Information

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