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Primaquine Dosage

When using primaquine to prevent malaria relapses, the manufacturer-recommended dosage is 26.3 mg once daily for 14 days. This medication is usually given after leaving a malaria area and is typically taken with food to help avoid an upset stomach. Even if you feel better within a couple of days, make sure to finish your prescribed amount.

An Introduction to Dosing With Primaquine

The dose of primaquine phosphate your healthcare provider recommends will depend on whether you have any other medical conditions.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

What Is the Primaquine Dose for Preventing Malaria Relapses?

The primaquine dose for preventing malaria relapses, based on the manufacturer's recommendation, is primaquine phosphate 26.3 mg once daily for 14 days. Primaquine phosphate 26.3 mg is equivalent to 15 mg of primaquine base (without the phosphate).
However, the Centers for Disease Control and Prevention (CDC) recommends a dosage of 52.6 mg primaquine phosphate (30 mg base) once daily for 14 days.

General Information on Taking Primaquine

Some considerations for people taking this medication include the following:
  • Primaquine comes in tablet form. It is usually taken once a day for 14 days in addition to another antimalarial medication.
  • This medication may be taken with or without food. It is usually taken with food to help prevent stomach upset.
  • Sometimes, the strength of this medication is listed in different terms. Primaquine phosphate 26.3 mg is equivalent to 15 mg of primaquine base (without the phosphate).
  • Primaquine is usually given after leaving a malaria area to prevent relapses of a malaria infection.
  • Although this medication can be crushed, it is extremely bitter tasting. Talk to your doctor or pharmacist about possible solutions to this problem if someone with difficulty swallowing the tablets, such as a child, needs to take this medication. Sometimes, the crushed medication can be mixed with something sweet, such as chocolate syrup or jelly.
  • Make sure to take primaquine at the same time each day to keep an even level of the medication in your bloodstream.
  • Make sure you continue to take this medication for the full treatment course, even if you start to feel better. Not finishing the medicine may cause your malaria to return.
  • For the medication to work properly, it must be taken as prescribed.

Primaquine Medication Information

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