Malarone Reactions

Headache, muscle pain, nausea, and stomach pain are some of the most commonly reported side effects in adults taking Malarone® (atovaquone/proguanil). Reactions to the malaria drug tend to be minor, and the side effects that do require treatment are often easy to treat.
 
However, more serious side effects have been known to occur, such as allergic reactions, seizures, or hallucinations. Skin reactions to Malarone are also possible. In rare cases, a person may develop a skin rash that is red, blistering, or peeling. If you develop any of these potentially dangerous problems, contact your healthcare provider right away.
 
(To learn more about potential reactions to this drug, click Malarone Side Effects. This article looks at how frequently side effects occurred in clinical trials and explains what to do if you experience potentially serious problems.)
 
Written by/reviewed by: Susan Lakey, PharmD, MPH
Last reviewed by: Kristi Monson, PharmD