Malaria Home > Quinine

Drug Interactions

Quinine can potentially interact with several other medicines (see Drug Interactions With Quinine).

What If I Take an Overdose of Quinine?

An overdose with quinine can be very dangerous, as it may cause vision problems (including permanent blindness), heart problems, or other serious problems. In some cases, a quinine overdose can cause life-threatening complications. If you happen to overdose on this medication, seek immediate medical attention.
(Click Quinine Overdose for more information.)

What Should I Do If I Miss a Dose?

If you forget to take a dose of quinine, and it has been more than four hours since the missed dose, simply skip your missed dose and continue with your regular dosing schedule.
If it has been less than four hours, take the missed dose and then resume with your regular dosing schedule. Do not take a double dose of this medicine or more than three doses in one day.

How Does This Medication Work?

Quinine belongs to a class of drugs called antimalarials. Malaria is a blood infection caused by tiny parasites called Plasmodium. Quinine treats malaria by killing the Plasmodium parasites.
Although it is not entirely known how quinine works, it is thought that the medication prevents Plasmodium from using blood glucose for energy and from making proteins and nucleic acid, which are essential for the parasite to live.

Clinical Effects of Quinine

The main active ingredient of this medication is quinine. Clinical studies have shown that quinine can cure malaria when given alone or in combination with clindamycin or tetracycline.
In these studies, 80 to 100 percent of people with uncomplicated (mild) malaria were free from infection after receiving quinine for seven days. They remained infection-free for the entire study period (28 days).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
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