Malaria Home > Quinine Dosage

The standard dosage of quinine for treating malaria is two capsules taken every eight hours for seven days. If you have kidney disease, you may need a lower dosage. You should start to feel better after a couple of days; however, do not stop taking the medication even though you feel better. This medication will not work unless it is taken as prescribed.

An Introduction to Your Dosage of Quinine

The dose of quinine sulfate (Qualaquin®) your healthcare provider recommends will depend on whether you have kidney disease. As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

Quinine Dosing for Treating Malaria

The standard quinine dosage for treating malaria is 648 mg (two capsules) every eight hours for seven days.
In people with severe kidney disease, the standard dosage is a one-time dose of 648 mg (two capsules), then 324 mg (one capsule) every 12 hours for seven days.

General Information on Taking Quinine

Some considerations for people taking quinine include the following:
  • This medication comes in capsule form. It is usually taken by mouth three times a day.
  • Quinine should be taken with food to reduce the chance that it will bother your stomach.
  • Try to take your doses about eight hours apart to keep an even level of the medication in your bloodstream.
  • Quinine is normally used in combination with one or more other medicines to treat malaria.
  • You should start to feel better within two days of beginning quinine treatment. However, do not stop taking this medication just because you feel better. Take it for as long as your healthcare provider tells you to.
  • This medication is normally taken for seven days to completely clear a malaria infection.
  • This medication is not approved to treat or prevent nighttime leg cramps, and should not be used for this reason. Taking quinine for nighttime leg cramps may lead to serious or life-threatening side effects.
  • For the medication to work properly, it must be taken as prescribed.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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