Malaria Home > Primaquine Warnings and Precautions

You may not be able to safely take primaquine if you have liver disease, kidney failure, or certain autoimmune diseases. Other warnings and precautions with primaquine apply to women who are pregnant or breastfeeding. Also, this medication may cause negative drug interactions with several other products, so tell your healthcare provider about any other prescription medicines, nonprescription medicines, or supplements you are taking.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking primaquine phosphate if you have:
 
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Kidney disease or kidney failure (renal failure)
  • Certain autoimmune diseases, such as rheumatoid arthritis or lupus erythematosus (lupus)
  • A genetic condition called glucose-6-phosphate dehydrogenase (G6PD) deficiency
  • A genetic condition called nicotinamide adenine dinucleotide (NADH) methemoglobin reductase deficiency
  • Methemoglobinemia (a blood disorder)
  • Ever had (or have a family member with) a reaction to eating fava beans
  • Ever had hemolytic anemia
  • Any allergies, including allergies to foods, dyes, or preservatives.
  •  
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
  •  
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
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