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Primaquine Drug Interactions ExplainedThe following sections explain in detail the potentially negative reactions that can occur when primaquine is combined with any of the drugs listed above.
Primaquine may increase the amount of alosetron in your blood, increasing your risk for potentially serious side effects. Talk to your healthcare provider before taking these medications together.
Taking primaquine with certain antidepressant medications may increase the level of the antidepressant in your body, increasing your risk for side effects. Not all antidepressants will interact with primaquine. Talk to your healthcare provider about this potential interaction before you take primaquine with an antidepressant.
Primaquine may increase the levels of some (but not all) antipsychotics in your body, increasing your risk for side effects. If you take these medications together, your healthcare provider may need to monitor you more closely for antipsychotic side effects.
Primaquine may increase the level of some beta blocker medications in your body, potentially lowering your blood pressure too much. If your blood pressure becomes too low, you may feel dizzy, lightheaded, or faint. Talk to your healthcare provider before taking primaquine with beta blocker medications. He or she may need to monitor your blood pressure more closely.
Certain Parasitic Medications
Primaquine may decrease the level of some parasitic medications in the blood, possibly making them less effective. Check with your healthcare provider before taking these medications together.
Taking primaquine with cyclobenzaprine may increase the level of cyclobenzaprine in your body, potentially increasing your risk for side effects. Talk to your healthcare provider about this interaction before you take primaquine with cyclobenzaprine.