Malarone® (atovaquone/proguanil) is a medication licensed for the treatment of malaria -- in particular, uncomplicated cases that are caused by a specific type of parasite. It can also be used in combination with certain measures (such as avoiding mosquitoes by using bed nets) to prevent malaria. It comes in tablet form and is usually taken once a day.
Among the conditions you should let your healthcare provider know about before you take this malaria drug are kidney disease, liver disease, and any allergies. Malarone, like any medicine, has the potential to cause side effects; however, most people tolerate it well. In clinical studies, the most commonly reported reactions included headache, stomach pain, and nausea.
(For more information on this malaria drug, click Malarone. This article tells you what you need to know about how to take it, other side effects, how it works, and more.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Malarone [package insert]. Research Triangle Park, NC: GlaxoSmithKline;2009 September.
Micromedex Healthcare Series [Internet database]. Greenwood Village, CO: Thomson Reuters (Healthcare), Inc. Updated periodically. Accessed October 4, 2010.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed October 4, 2010.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 8th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2008.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed October 5, 2010.
National Library of Medicine (US). Hazardous Substances Data Bank (HSDB). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB. Accessed October 5, 2010.
Centers for Disease Control and Prevention. CDC Health Information for International Travel 2010. Atlanta: U.S. Department of Health and Human Services, Public Health Service, 2009.
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