Available by prescription only, Coartem® (artemether/lumefantrine) is a medicine used to treat malaria. Specifically, this medication is used to treat mild cases of malaria, also called uncomplicated malaria. Coartem is used for malaria treatment; it is not effective at preventing the malaria blood infection from occurring.
As an antimalarial medication, Coartem works by killing the parasites that cause this blood infection. It is believed that Coartem prevents the bacteria from using blood glucose for energy and from making proteins and nucleic acid, which are essential for the parasites to live.
(For more information on using this drug for malaria, click Coartem. This article also discusses potential side effects of the drug, dosing information, and safety precautions to be aware of before beginning treatment.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Coartem [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corporation;2012 August.
Micromedex Healthcare Series [Internet database]. Greenwood Village, CO: Thomson Reuters (Healthcare), Inc. Updated periodically. Accessed October 6, 2010.
World Health Organization. Management of Severe Malaria: A Practical Handbook, 2nd edition. World Health Organization, Geneva, 2000.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed October 8, 2010.
National Library of Medicine (US). Hazardous Substances Data Bank (HSDB). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB. Accessed October 8, 2010.
Centers for Disease Control and Prevention. CDC Health Information for International Travel 2010. Atlanta: U.S. Department of Health and Human Services, Public Health Service, 2009.
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