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More Details on Drug Interactions With Chloroquine

The following sections explain in detail the potentially negative interactions that can occur when chloroquine is combined with any of the drugs listed above.
Agalsidase Beta
Chloroquine may make agalsidase beta less effective. Talk to your healthcare provider before using these medications together.
Chloroquine may decrease the amount of ampicillin in the body, potentially making it less effective. The manufacturer of chloroquine recommends that these medications be separated by at least two hours to reduce the chance of this drug interaction.
Taking antacids with chloroquine may decrease the amount of chloroquine your body absorbs. You should avoid using antacids within four hours of taking your chloroquine dosage to reduce the risk of this drug interaction.
Beta Blockers
Chloroquine may increase the level of some beta blocker medications in your body, potentially lowering your blood pressure too much. If your blood pressure becomes too low, you may feel dizzy, lightheaded, or faint. Talk to your healthcare provider before taking chloroquine with beta blocker medications. He or she may need to monitor your blood pressure more closely.
Certain Parasitic Medications
Chloroquine may decrease the level of some parasite medications in the blood, possibly making them less effective. Check with your healthcare provider before taking these medications together.
Chloroquine may make codeine less effective at controlling pain. If you take these medications together, you may notice that codeine does not work as well to relieve your pain. Talk to your healthcare provider about possible options for pain relief while you take chloroquine.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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