Your age, weight, and purpose for using Lariam (either to prevent or treat malaria) will help your healthcare provider determine the best dosage for your situation. This medication comes in tablet form and is either taken as a one-time dose (to treat malaria) or once weekly for several weeks (to prevent malaria).
The dose of Lariam® (mefloquine hydrochloride) your healthcare provider recommends will vary depending on a number of factors, including:
- Whether you are taking the medication to prevent or to treat malaria
- Your age
- Your weight (in children).
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
The standard dosage for malaria prevention is 250 mg of Lariam, taken once a week. Treatment usually begins one to three weeks before traveling to an area where you might get malaria, continues weekly while you are in the malaria area, and for four weeks after leaving the area.
The usual dosage of Lariam for preventing malaria in children who weigh 45 kg (about 99 pounds) or less is based on the child's weight. Children who weigh more than 45 kg are given the adult dose. Just like adults, children will need to take Lariam before, during, and after travel to prevent malaria.
The standard dosage of Lariam for treating malaria in adults is 1250 mg in one dose.
The standard dose in children is based on the child's weight. Children are usually given 20 mg to 25 mg of Lariam per kg of body weight. Children may take the medication in two doses, given six to eight hours apart, to help reduce the chance of side effects, such as vomiting.