Coartem Warnings and Precautions

You may not be able to safely take Coartem if you have certain problems with your heart, liver, or kidneys. Other warnings and precautions with Coartem apply to women who are pregnant or breastfeeding. Also, this medication may cause negative drug interactions with several other products, so tell your healthcare provider about any other prescription medicines, nonprescription medicines, or supplements you are taking.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Coartem® (artemether/lumefantrine) if you have:
 
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Kidney disease, such as kidney failure (renal failure)
  • Heart disease, such as congestive heart failure or a family history of heart problems
  • Heart rhythm problems, including atrial fibrillation (afib), QT prolongation, or a history of an abnormal electrocardiogram (ECG)
  • Low blood electrolytes, such as low blood potassium (hypokalemia) or magnesium (hypomagnesemia)
  • Any allergies, including allergies to foods, dyes, or preservatives.
     
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
     
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
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Written by/reviewed by: Susan Lakey, PharmD, MPH
Last reviewed by: Kristi Monson, PharmD
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