Mode of Action of Chloroquine
Most people get malaria from the bite of an infected female Anopheles mosquito. Through the bite, a microscopic parasite called Plasmodium enters the body and causes infection, with malaria symptoms typically appearing 10 to 30 days after a person becomes infected.
Chloroquine phosphate (Aralen®) works by killing the Plasmodium parasites that cause the infection. How does it kill the parasites? Chloroquine's mode of action is not entirely clear -- however, it is possible that the drug stops the parasites from reproducing by interfering with their DNA.
(Click Chloroquine to learn more about the drug's mode of action. This article also tells you about possible side effects, safety warnings, dosing guidelines, and more.)