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Chloroquine Dosage

To prevent malaria, chloroquine tablets must be taken before, during, and after travel to a malaria zone. When treating the condition in adults, chloroquine is usually taken twice a day for one day and then once a day for two more days. A child's chloroquine dosage will be determined by his or her weight. Taking the medicine with food can help prevent an upset stomach.

An Introduction to Dosing With Chloroquine

The dose of chloroquine phosphate (Aralen®) your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • The reason you are taking chloroquine
  • Other medical conditions you may have
  • Your weight.
     
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
 

What Is the Chloroquine Dosage for Preventing Malaria?

The usual dosage for malaria prevention in adults is 500 mg once a week. The chloroquine dose in children is based on the child's weight. Children either receive about 8.3 mg per kg of body weight (about 3.8 mg per pound of body weight) or the adult dose, whichever is less.
 
Treatment usually begins two weeks before traveling to an area where you might get malaria, continues weekly while you are in the area, and for eight weeks after leaving the area.
 
If treatment does not begin two weeks prior to travel, an initial larger dose (called a "loading dose") is given instead. In adults, the loading dosage of chloroquine is 1000 mg. In children, the loading dose is about 16.7 mg per kg of body weight (about 7.6 mg per pound of body weight), which can be divided into two doses taken six hours apart.
 

What Is the Chloroquine Dosage for Treating Malaria?

The standard chloroquine dose for treating malaria in adults is a one-time loading dose of 1000 mg, followed by 500 mg in six to eight hours. Then 500 mg is taken once a day for two more days.
 
The standard dosage for malaria treatment in children is based on the child's weight. Children are usually given a loading dose of 16.7 mg per kg body weight (about 7.6 mg per pound of body weight), followed by 8.3 mg per kg (about 3.8 mg per pound) at 6, 24, and 36 hours after the loading dose. However, a child should never receive more than the adult dosage.
 

Chloroquine Drug Information

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